Pharma API 99% Pure NAD+ Supplementation CAS No 53-84-9

Product Description:

β-Nicotinamide Adenine Dinucleotide (NAD+) is an essential coenzyme found in every living cell. It plays a key role in cellular metabolism, energy production, and maintaining overall cellular health. NAD+ is crucial for the process of converting food into energy through cellular respiration, particularly in the mitochondria, which produce ATP, the primary energy source for cells. Additionally, NAD+ is involved in DNA repair, gene expression regulation, and maintaining the integrity of cellular structures.

As we age, the levels of NAD+ in the body naturally decrease, which can lead to various age-related health issues, including reduced energy, cognitive decline, and a weakened immune response. This decline in NAD+ levels has also been linked to increased inflammation, oxidative stress, and impaired cellular repair mechanisms. Therefore, boosting NAD+ levels has become a popular approach to potentially counteract these age-related declines and promote healthier aging.

NAD+ also activates certain enzymes known as sirtuins, which help to regulate cellular functions such as inflammation, repair of damaged cells, and stress resistance. These processes have been associated with improved longevity and overall health. Given its vital role in maintaining cellular function and its potential to support healthy aging, NAD+ has gained significant attention for its therapeutic benefits in treating age-related diseases and promoting well-being.

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Applications of NAD+:

Nicotinamide Adenine Dinucleotide (NAD+) has several important applications across various fields, including health, research, and therapeutic interventions:

1. Anti-Aging and Longevity: NAD+ has garnered attention for its potential anti-aging effects. Increasing NAD+ levels, either through precursors like NMN (Nicotinamide Mononucleotide) or direct supplementation, is believed to support mitochondrial function, enhance DNA repair mechanisms, and promote overall cellular health. This has led to the development of NAD+ boosting supplements and therapies aimed at potentially extending lifespan and improving health span.

2. Metabolic Health: NAD+ plays a crucial role in cellular metabolism, particularly in the conversion of nutrients into energy. Research suggests that maintaining optimal NAD+ levels could potentially help in managing metabolic disorders such as obesity, diabetes, and metabolic syndrome. Therapeutic approaches targeting NAD+ metabolism are being explored for their potential to mitigate metabolic dysfunction.

3. Neurological Disorders: NAD+ is implicated in neuronal health and function. Studies have shown that NAD+ levels decline in neurodegenerative diseases such as Alzheimer's and Parkinson's. Boosting NAD+ levels through supplementation or activating NAD+-dependent pathways may have therapeutic potential in protecting neurons from degeneration and improving cognitive function.

4. Cardiovascular Health: NAD+ is involved in cardiovascular function, including regulation of vascular tone, endothelial function, and cardiac metabolism. Research indicates that maintaining adequate NAD+ levels could potentially protect against cardiovascular diseases such as hypertension, atherosclerosis, and heart failure. Therapeutic strategies targeting NAD+ pathways are being investigated for their cardiovascular benefits.

5. Cancer Therapy: NAD+ metabolism is closely linked to cellular processes that are dysregulated in cancer cells. Modulating NAD+ levels or targeting NAD+-dependent enzymes involved in DNA repair and cellular survival pathways is being explored as a potential strategy for cancer therapy. Preclinical studies suggest that manipulating NAD+ metabolism could sensitize cancer cells to chemotherapy or radiation therapy.

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