High-Quality Chemical Pharmaceutical Grade Tianeptine Acid Factory Price CAS 66981-73-5

Product Description:

Tianeptine Acid Powder (CAS 66981-73-5) is a chemical compound derived from Tianeptine, an antidepressant widely used for treating major depressive disorder (MDD) and anxiety. It is considered a metabolite or derivative of Tianeptine, which itself has well-documented neurobiological properties, particularly in the modulation of serotonin and brain-derived neurotrophic factor (BDNF).

Tianeptine Acid has a structure closely related to its parent compound, Tianeptine, but features modifications that alter its solubility, bioavailability, and potential pharmacological effects. This modification of the chemical structure allows researchers to study the potential impacts of Tianeptine derivatives on the central nervous system (CNS) without directly administering the original Tianeptine. As a powder, Tianeptine Acid is highly soluble and can be easily formulated into various experimental preparations for testing in pharmacological studies.

While Tianeptine is an established antidepressant, Tianeptine Acid’s exact pharmacological role is not yet fully understood. It is believed that the compound may have a neuroprotective effect, potentially supporting the brain's stress response system. It has been suggested that Tianeptine and its derivatives may help mitigate neuroinflammation and oxidative stress, both of which are associated with mood disorders, neurodegenerative diseases, and cognitive decline. Tianeptine Acid, like Tianeptine, may play a role in enhancing cognitive function, promoting memory formation, and even improving cerebral blood flow.

Moreover, early studies have hinted that Tianeptine Acid could act as a glutamate modulator, which may offer neuroprotective benefits in the context of chronic stress, a known contributor to neurodegenerative diseases like Alzheimer's and Parkinson's.

Function:

1. Antidepressant Properties: Tianeptine acid, like its salt forms, is recognized for its antidepressant effects. It works through an atypical mechanism, acting as a selective serotonin reuptake enhancer (SSRE). Unlike traditional antidepressants that block serotonin reuptake, tianeptine enhances its reabsorption, which helps balance mood and alleviate symptoms of depression.

2. Modulation of Glutamate Activity: Tianeptine acid also regulates glutamatergic transmission, particularly through AMPA and NMDA receptors. This modulation plays a critical role in reducing stress-related neural damage and improving neuroplasticity, which is often impaired in mood disorders like depression.

3. Neuroprotective Effects: By enhancing neuroplasticity and reducing the damaging effects of stress on neurons, tianeptine acid is associated with neuroprotection. This can help in preserving cognitive functions and mitigating cognitive decline in individuals with depressive disorders.

4. Anxiolytic Properties: Tianeptine acid shows significant anxiolytic (anti-anxiety) effects, reducing symptoms of anxiety by modulating neurotransmitter activity in the brain, particularly in stress-induced or anxiety-prone individuals.

Dosage:

Tianeptine acid (CAS 66981-73-5) is the free acid form of tianeptine, and its dosage can vary depending on its application, particularly in research or preclinical settings. However, tianeptine sodium and tianeptine sulfate are the most commonly studied and prescribed forms, and their dosing guidelines can provide a reference point. Since the bioavailability and pharmacokinetics of tianeptine acid differ from these forms, the dosage for the acid form would need to be adjusted.

General Dosage Considerations:

Tianeptine Sodium: The usual recommended dose for tianeptine sodium is 12.5 mg taken three times per day for the treatment of depression and anxiety.

Tianeptine Sulfate: Due to its slower release and longer half-life, tianeptine sulfate is typically taken at 25-50 mg once or twice per day.
Tianeptine Acid Dosage:

The exact dosage of tianeptine acid (CAS 66981-73-5) is less established in clinical literature due to its less common use compared to the sodium and sulfate forms. If tianeptine acid is being used in research or experimental settings, the dosage is usually determined by the specific goals of the study, focusing on pharmacodynamic and pharmacokinetic parameters. The conversion from tianeptine sodium or sulfate to tianeptine acid is not straightforward because the acid form might have different absorption rates and bioavailability.

Packing and Shipping:

1~25kgs packaging: Aluminium bag inside, Carton box outside.

25kgs packaging: Plastic bag inside, Fiber drum outside

FAQ:

1.What's your MOQ?
Our MOQ is flexible, usually 10 grams~50 grams for a trial order is acceptable.

2. How to deliver the goods?
≤50kg ship by FedEx/UPS, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

3. What is the shelf life for the products?
Most products shelf life 24-36 months.

4. What's your delivery time?
Usually, shipment will be made within 1-3 days against confirmed order.

5. How about the validity of the offer?
Usually, our offer is valid for 2 week. However, validity might vary between different products.