Wholesale High Purity Tianeptine Acid Treatment For Depression CAS 66981-73-5

Product Description:

Tianeptine acid (CAS 66981-73-5) is the free acid form of tianeptine, a tricyclic antidepressant known for its distinct pharmacological profile. Unlike its more prevalent derivatives, such as tianeptine sodium and tianeptine sulfate, tianeptine acid exhibits lower solubility in water, which can influence its absorption and overall bioavailability in the body. This form is primarily of interest in research settings, where it is studied to better understand its mechanisms of action and potential therapeutic applications.

The primary function of tianeptine acid is its role as an antidepressant. It operates through a unique mechanism compared to traditional antidepressants. While most antidepressants inhibit the reuptake of serotonin, tianeptine acid enhances serotonin reabsorption, categorizing it as a selective serotonin reuptake enhancer (SSRE). This distinctive action helps restore balance in serotonin levels, which can significantly improve mood and alleviate symptoms of depression.

In addition to its antidepressant effects, tianeptine acid is recognized for its anxiolytic properties, effectively reducing anxiety and promoting overall emotional stability. This makes it beneficial for individuals who experience anxiety in conjunction with depression.

Another significant function of tianeptine acid is its influence on the glutamatergic system. It modulates the activity of glutamate, the primary excitatory neurotransmitter in the brain, particularly through interactions with AMPA and NMDA receptors. By enhancing glutamatergic transmission, tianeptine acid promotes neuroplasticity, which is essential for cognitive flexibility and resilience to stress. This neuroprotective effect helps safeguard neurons from damage associated with chronic stress, thereby supporting brain health and function.

Tianeptine acid is primarily used in pharmaceutical research to explore its unique properties, comparing its efficacy and safety profiles to those of other forms of tianeptine. Researchers focus on its potential to inform new therapeutic strategies for treating mood disorders and its role in enhancing cognitive function.

In conclusion, tianeptine acid (CAS 66981-73-5) is a promising compound with significant antidepressant, anxiolytic, and neuroprotective properties. Its unique mechanisms of action make it a valuable subject for ongoing research aimed at improving treatment options for individuals suffering from depression and anxiety.

Dosage:

Tianeptine acid (CAS 66981-73-5) is the free acid form of tianeptine, and its dosage can vary depending on its application, particularly in research or preclinical settings. However, tianeptine sodium and tianeptine sulfate are the most commonly studied and prescribed forms, and their dosing guidelines can provide a reference point. Since the bioavailability and pharmacokinetics of tianeptine acid differ from these forms, the dosage for the acid form would need to be adjusted.

General Dosage Considerations:

Tianeptine Sodium: The usual recommended dose for tianeptine sodium is 12.5 mg taken three times per day for the treatment of depression and anxiety.

Tianeptine Sulfate: Due to its slower release and longer half-life, tianeptine sulfate is typically taken at 25-50 mg once or twice per day.
Tianeptine Acid Dosage:

The exact dosage of tianeptine acid (CAS 66981-73-5) is less established in clinical literature due to its less common use compared to the sodium and sulfate forms. If tianeptine acid is being used in research or experimental settings, the dosage is usually determined by the specific goals of the study, focusing on pharmacodynamic and pharmacokinetic parameters. The conversion from tianeptine sodium or sulfate to tianeptine acid is not straightforward because the acid form might have different absorption rates and bioavailability.

Packing and Shipping:

1~25kgs packaging: Aluminium bag inside, Carton box outside.

25kgs packaging: Plastic bag inside, Fiber drum outside

FAQ:

1.What's your MOQ?
Our MOQ is flexible, usually 10 grams~50 grams for a trial order is acceptable.

2. How to deliver the goods?
≤50kg ship by FedEx/UPS, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

3. What is the shelf life for the products?
Most products shelf life 24-36 months.

4. What's your delivery time?
Usually, shipment will be made within 1-3 days against confirmed order.

5. How about the validity of the offer?
Usually, our offer is valid for 2 week. However, validity might vary between different products.