Manufacturer And Supplier Of Tianeptine Acid CAS 66981-73-5 For Anxiety Treatment

Product Description:

Tianeptine acid (CAS 66981-73-5) is the free acid form of the tianeptine molecule, a compound known for its antidepressant and anxiolytic effects. Unlike tianeptine sodium or sulfate, which are more commonly used in clinical applications due to better water solubility and bioavailability, tianeptine acid is primarily used in research settings.

Tianeptine acid works by modulating serotonin reuptake and glutamate activity, offering a unique approach to treating depression and anxiety. It enhances neuroplasticity, protecting brain cells from stress-induced damage, and can improve cognitive functions in individuals with mood disorders. While not typically prescribed in medical settings, tianeptine acid plays a key role in understanding the pharmacokinetics and pharmacodynamics of tianeptine for drug development and optimization studies. Its different solubility profile compared to salt forms makes it a focus of investigation in terms of absorption and drug delivery systems.

Function:

Tianeptine acid (CAS 66981-73-5) functions similarly to its salt derivatives, exhibiting antidepressant and anxiolytic properties. It acts as a selective serotonin reuptake enhancer (SSRE), which increases the reabsorption of serotonin, unlike typical antidepressants that block reuptake. This unique mechanism helps regulate mood and alleviate symptoms of depression. Additionally, tianeptine acid influences glutamatergic transmission, modulating AMPA and NMDA receptors, which is essential in promoting neuroplasticity and reducing the negative effects of stress on the brain.

The compound also has neuroprotective effects, safeguarding neurons from stress-induced damage, and can support cognitive function improvement, particularly in individuals affected by mood disorders. While it is not commonly used in clinical settings due to solubility differences, it is a valuable tool in pharmaceutical research, exploring its potential for developing new antidepressant formulations and drug delivery methods. Its pharmacokinetic profile offers insights into absorption rates and bioavailability when compared to tianeptine sodium or sulfate.

Dosage:

Tianeptine acid (CAS 66981-73-5) is the free acid form of tianeptine, and its dosage can vary depending on its application, particularly in research or preclinical settings. However, tianeptine sodium and tianeptine sulfate are the most commonly studied and prescribed forms, and their dosing guidelines can provide a reference point. Since the bioavailability and pharmacokinetics of tianeptine acid differ from these forms, the dosage for the acid form would need to be adjusted.

General Dosage Considerations:

Tianeptine Sodium: The usual recommended dose for tianeptine sodium is 12.5 mg taken three times per day for the treatment of depression and anxiety.

Tianeptine Sulfate: Due to its slower release and longer half-life, tianeptine sulfate is typically taken at 25-50 mg once or twice per day.
Tianeptine Acid Dosage:

The exact dosage of tianeptine acid (CAS 66981-73-5) is less established in clinical literature due to its less common use compared to the sodium and sulfate forms. If tianeptine acid is being used in research or experimental settings, the dosage is usually determined by the specific goals of the study, focusing on pharmacodynamic and pharmacokinetic parameters. The conversion from tianeptine sodium or sulfate to tianeptine acid is not straightforward because the acid form might have different absorption rates and bioavailability.

Packing and Shipping:

1~25kgs packaging: Aluminium bag inside, Carton box outside.

25kgs packaging: Plastic bag inside, Fiber drum outside

FAQ:

1.What's your MOQ?
Our MOQ is flexible, usually 10 grams~50 grams for a trial order is acceptable.

2. How to deliver the goods?
≤50kg ship by FedEx/UPS, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

3. What is the shelf life for the products?
Most products shelf life 24-36 months.

4. What's your delivery time?
Usually, shipment will be made within 1-3 days against confirmed order.

5. How about the validity of the offer?
Usually, our offer is valid for 2 week. However, validity might vary between different products.