Pharmaceutical Intermediate Anti-Pain CAS 137-58-6 Local Anesthesia Raw Powder Lidocaine for Pain Killer

Product Description:

Lidocaine is an amide-type local anesthetic that inhibits the ionic fluxes required for the initiation and conduction of impulses. This stabilizes the neuronal membrane and affects local anesthetic action. Lidocaine is currently available as an external cream, intradermal injectable powder, external gel, ophthalmic gel, external jelly, external lotion, external ointment, external patch, injection solution, and topical solution.

Technical Parameters:

Function

1. The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action.

2. Epinephrine vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

3. Relative insensitivity to lidocaine is genetic. In hypokalemic sensory overstimulation, relative insensitivity to lidocaine has been described in people who also have attention deficit hyperactivity disorder.In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.

4. Lidocaine, along with ethanol, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

Application

1. Local Anesthesia:

Lidocaine is widely used for local anesthesia to numb specific areas of the body during medical procedures, surgeries, dental work, and minor skin treatments (e.g., skin biopsies).
It is available in various formulations such as creams, gels, sprays, solutions for injection, and patches.

2. Pain Management:

Beyond local anesthesia, lidocaine is used to manage pain associated with conditions like post-herpetic neuralgia (nerve pain following shingles) and other chronic pain syndromes.
Lidocaine patches are often used for their convenience in providing localized pain relief over extended periods.

3. Cardiac Arrhythmias:

Lidocaine is also used intravenously in emergency medicine and cardiology to treat certain types of irregular heart rhythms (arrhythmias), particularly ventricular arrhythmias.

Packing and Shipping:

1~25kgs packaging: Aluminium bag inside, Carton box outside.

25kgs packaging: Plastic bag inside, Fiber drum outside

FAQ:

1.Can I get samples for testing?

Yes, sample can be provided, but you will need to pay the freight.

2.What's the delivery leadtime?

3-7 days by air after payment, if it is by sea, the shipment time should be determined according to the shipping date.

3. What is the shelf life for the products?
Most products shelf life 24-36 months.

4. What's your delivery time?
Usually, shipment will be made within 1-3 days against confirmed order.

5. How about the validity of the offer?
Usually, our offer is valid for 2 week. However, validity might vary between different products.