Product Details
Place of Origin: China
Brand Name: Quickoolchem
Payment & Shipping Terms
Minimum Order Quantity: 50 Grams
Price: Negotiable
Packaging Details: 1~10 KG Aluminum Foil Bag, 25KG/drum
Delivery Time: 1-3 working day
Payment Terms: L/C, D/A, D/P, T/T, Western Union, MoneyGram
Supply Ability: 10 MT/Month
Assay: |
HPLC 99%, 98%min, 99.0~101.0% |
Cas: |
171596-29-5 |
Coa: |
Available |
Appearance: |
White To Off-white Powder |
Function: |
Sex Enhancement |
Package: |
25kg/drum |
Purity: |
≥99% |
Sample: |
Available |
Service: |
Professional & Rich Experience |
Shelf Life: |
2 Years |
Shipping Method: |
Air(UPS, FedEx, TNT, EMS) Or Sea |
Storage: |
Store In A Cool, Dry Place |
Test Method: |
HPLC UV |
Molecular Formula: |
C22H19N3O4 |
Molecular Weight: |
389.404 |
Quality: |
Pharmaceutical |
Assay: |
HPLC 99%, 98%min, 99.0~101.0% |
Cas: |
171596-29-5 |
Coa: |
Available |
Appearance: |
White To Off-white Powder |
Function: |
Sex Enhancement |
Package: |
25kg/drum |
Purity: |
≥99% |
Sample: |
Available |
Service: |
Professional & Rich Experience |
Shelf Life: |
2 Years |
Shipping Method: |
Air(UPS, FedEx, TNT, EMS) Or Sea |
Storage: |
Store In A Cool, Dry Place |
Test Method: |
HPLC UV |
Molecular Formula: |
C22H19N3O4 |
Molecular Weight: |
389.404 |
Quality: |
Pharmaceutical |
Product name | Tadalafil API Powder |
Appearance | White crystalline powder |
CAS | 171596-29-5 |
MF | C22H19N3O4 |
Purity | 99% |
Storage |
Keep in cool dry place. |
Tadalafil API powder refers to the active pharmaceutical ingredient (API) in the medication Tadalafil. Tadalafil is a medication primarily used to treat erectile dysfunction (ED) and symptoms of benign prostatic hyperplasia (BPH). It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors.
The API powder is the pure form of tadalafil, which is the chemical compound responsible for the therapeutic effects of the medication. Pharmaceutical companies use this powder as the key ingredient in formulating Tadalafil tablets or other dosage forms. The powder is carefully manufactured and tested to ensure purity, potency, and safety for use in pharmaceutical products.
The application and function of Tadalafil API powder primarily revolve around its use in the pharmaceutical industry to produce medications for the treatment of erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). Here's a breakdown:
1. Treatment of Erectile Dysfunction (ED): Tadalafil API powder is the active ingredient in medications like Cialis. It works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which regulates blood flow to the penis. By inhibiting PDE5, tadalafil promotes relaxation of the smooth muscles in the blood vessels of the penis, allowing for increased blood flow and thus facilitating erections. This makes it effective in treating erectile dysfunction in men.
2. Treatment of Benign Prostatic Hyperplasia (BPH): Tadalafil is also used in the treatment of symptoms associated with BPH, a condition characterized by an enlarged prostate gland. In BPH, tadalafil helps relax the smooth muscles in the prostate and bladder, which can alleviate symptoms like difficulty urinating, frequent urination, and urgency.
3. Pulmonary Arterial Hypertension (PAH): Tadalafil is sometimes used off-label in the treatment of pulmonary arterial hypertension, a condition characterized by high blood pressure in the arteries of the lungs. It works by relaxing the blood vessels in the lungs to allow blood to flow more easily, thereby reducing the workload on the heart.
Overall, the primary function of tadalafil API powder is to serve as the active pharmaceutical ingredient in medications designed to treat various conditions related to vascular function and smooth muscle relaxation, particularly erectile dysfunction and benign prostatic hyperplasia.
The usage and dosage of Tadalafil API powder are determined by pharmaceutical manufacturers during the formulation of Tadalafil-based medications, such as tablets or capsules. It's essential to follow the prescribed dosage and administration instructions provided by healthcare professionals or as indicated on the medication label. Here's a general overview:
1. Dosage Strengths: Tadalafil API powder is available in various dosage strengths, typically ranging from 2.5 mg to 20 mg per tablet or capsule.
2. Treatment of Erectile Dysfunction (ED): The typical starting dose for the treatment of erectile dysfunction in adult males is 10 mg taken orally, as needed, prior to sexual activity. The dose may be adjusted based on individual response and tolerability, with a maximum recommended dose of 20 mg once daily. It's important not to exceed the recommended dosage or frequency of use.
3. Treatment of Benign Prostatic Hyperplasia (BPH) and ED/BPH: For the treatment of benign prostatic hyperplasia with concomitant erectile dysfunction, the recommended dose is 5 mg once daily, taken at approximately the same time each day.
4. Pulmonary Arterial Hypertension (PAH): When used off-label for the treatment of pulmonary arterial hypertension, the dosage may vary depending on factors such as the severity of the condition and individual patient response. Healthcare providers will determine the appropriate dose based on specific patient needs.
5. Special Populations: Dosage adjustments may be necessary for individuals with hepatic impairment or renal impairment, as tadalafil metabolism may be affected in these populations. Additionally, dosage adjustments may be required for elderly patients.
6. Administration: Tadalafil tablets or capsules should be swallowed whole with a glass of water and can be taken with or without food. It's essential to avoid crushing, breaking, or chewing the tablets.
7. Interactions: Tadalafil may interact with certain medications, including nitrates, alpha-blockers, antihypertensives, and other drugs metabolized by the cytochrome P450 enzyme system. Patients should inform their healthcare provider about all medications they are taking to avoid potential drug interactions.
Product | Tadalafil | |
Batch No. | 20240123 | |
Mfg. date | 20240125 | |
Perform standard | USP & EP | |
ANALYSIS | STANDARD | RESULT OF ANALYSIS |
Description | White to class white powder | Class white powder |
Solubility | Freely soluble in dimethyl sulfoxide, slightly soluble in methylene chloride, practically insoluble in water. | Conforms |
Specific rotation | +78.0°~84.0° | +82.1° |
Identification | HPLC | Conforms |
Ordinary impurities(Do not calculate isomer A+C) | Single impurity≤0.15% | 0.08% |
Total impurities≤1.0% | 0.42% | |
Calculate isomer | A≤0.3% | 0.21% |
B≤0.1% | Not detected | |
C≤0.1% | Not detected | |
Loss on drying | ≤0.5% | 0.35% |
Residue on ignition | ≤0.1% | Conforms |
Heavy metal | 20ppm | Conforms |
Assay | 97.5%~102.0% | 99.6% |
Conclusion:Conform to USP & EP |
1~25kgs packaging: Aluminium bag inside, Carton box outside.
25kgs packaging: Plastic bag inside, Fiber drum outside
Quickool Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, and herbal extracts.
Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
1.Can I get samples for testing?
Yes, sample can be provided, but you will need to pay the freight.
2.What's the delivery leadtime?
3-7 days by air after payment, if it is by sea, the shipment time should be determined according to the shipping date.
3. What is the shelf life for the products?
Most products shelf life 24-36 months.
4. What's your delivery time?
Usually, shipment will be made within 1-3 days against confirmed order.
5. How about the validity of the offer?
Usually, our offer is valid for 2 week. However, validity might vary between different products.