Product Description:
Tirzepatide powder is the active pharmaceutical ingredient of Tirzepatide, a novel synthetic peptide designed for the treatment of type 2 diabetes and potentially for obesity management. As a dual agonist of the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors, Tirzepatide enhances the body’s natural insulin response, decreases glucagon secretion, and slows gastric emptying. These actions work synergistically to improve glycemic control and facilitate weight loss in patients. The powder form is primarily used in pharmaceutical manufacturing, where it undergoes precise formulation into injectable medications for clinical application. Tirzepatide is administered through subcutaneous injections, with dosages typically starting low and gradually increased based on patient response and tolerance. The introduction of Tirzepatide marks a significant advancement in diabetes treatment, offering patients a new mechanism of action that not only targets blood sugar levels but also addresses weight management. As research continues, Tirzepatide shows promise for broader applications in metabolic health, potentially transforming the therapeutic landscape for individuals with type 2 diabetes.
Technical Parameters:
| Products Name: | Tirzepatide |
| CAS No.: | 2023788-19-2 |
| Purity: | ≥99.5% |
| Appearance: | White Lyophilized powder |
| Logo printing: | Available |
| Storage: | Cool Dry Place |
Dosage:
The dosage of Tirzepatide for treating type 2 diabetes, typically follows a gradual titration to minimize side effects and optimize effectiveness. It is administered via subcutaneous injection once weekly.
Here’s a general dosing schedule:
1. Starting dose: 2.5 mg once a week for the first 4 weeks. This low dose helps the body adjust to the medication.
2. Dose escalation:
After 4 weeks at 2.5 mg, the dose is increased to 5 mg once weekly.
If further blood sugar control is needed, the dose may be increased in 2.5 mg increments every 4 weeks, up to a maximum dose of 15 mg per week.
Titration schedule:
Week 1–4: 2.5 mg weekly
Week 5–8: 5 mg weekly
After 8 weeks: Based on effectiveness and tolerance, the dose may be increased to 7.5 mg, 10 mg, 12.5 mg, or 15 mg.
The dosage is tailored to the individual patient’s needs and response to the medication. Higher doses may offer additional benefits for glucose control and weight loss, but they also increase the likelihood of gastrointestinal side effects, such as nausea or diarrhea.
Patients should follow the dosage prescribed by their healthcare provider to ensure safety and efficacy.
Applications:
Tirzepatide is a novel medication with multiple functions, primarily used for the treatment of type 2 diabetes and showing potential for weight loss. Its main functions are:
1. Blood Glucose Regulation:
Tirzepatide acts as a dual agonist of GLP-1 (glucagon-like peptide-1) receptor and GIP (glucose-dependent insulinotropic polypeptide) receptor. By stimulating these two receptors, it enhances the body's natural production of insulin in response to elevated blood sugar, particularly after meals.
It also reduces the secretion of glucagon, a hormone that raises blood sugar levels, which helps to lower and stabilize glucose levels in the bloodstream.
2. Slows Gastric Emptying:
Tirzepatide delays the emptying of the stomach, leading to a slower release of glucose into the bloodstream. This helps prevent spikes in blood sugar after eating.
3. Weight Loss:
Because Tirzepatide targets both GLP-1 and GIP receptors, it has been found to promote significant weight loss in patients. It reduces appetite and increases satiety, making individuals feel fuller for longer periods, contributing to reduced food intake and weight management.
4. Cardiovascular Benefits:
The blood sugar-lowering effects of Tirzepatide, combined with its potential for weight reduction, also offer cardiovascular benefits by improving overall metabolic health, which may help reduce the risk of heart disease.
Overall, Tirzepatide provides an effective approach to improving blood sugar control in type 2 diabetes patients, while also promoting weight loss and improving other metabolic outcomes.
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